Industrial Consultancy & Sponsored Research (IC&SR) , IIT Madras
Laser Speckle Fiberscope for Detection of Extent of Cancerous Tissue and Methods thereof
Technology Category/Market
Technology: Laser Speckle Fiberscope ;
Industry: Medical & Surgical Device; Applications: Colonoscopy, Bronchoscopy, Vascular Fibroscopy, etc.;
Market: The global fiberscope market size is projected at a CAGR of 8.56% during period of 2022-2027.
Image
Problem Statement
- In present era, Cancer has become a major health problem & the main factor during surgical removal as well as biopsy procedures is the precise sampling of the tumor areas.
- Laser speckle contrast imaging(LSCI) has been used for analyzing tissue perfusion qualitatively, & the major challenge herein is the susceptibility of the LSCI to sample & experimental parameters. A few prior arts techniques have been discussed however unable to provide solutions as discussed in the present invention.
- Hence, there is a need to address above challenges in effective manner.
Technology
- Present invention describes a laser fiberscope device for assessment of tissue stiffness and tissue blood flow in-vivo.
- The claimed device further includes a laser light source, a position sensor controller, a microscope objective, a charge coupled device (CCD) camera with zoom lens and a personal computer (PC).
- The computing device comprises a machine learning algorithm configured to perform analysis on the acquired speckle image to assess tissue stiffness or tissue blood flow or both.
- Said device is configured to be introduced via an endoscope & the processing the image using speckle image analysis.
- Further, the proposed invention is also described a method of simultaneously assessing tissue stiffness & tissue blood flow in-vivo.
- The process is shown in figure 2 in step by step and the experimental setup including results are shown in Figs. 3 & 4.
Key Features/Value Proposition
Technical Perspective:
- A static scattering coefficient of tissues is estimated independent of flow velocities using a machine learning model.
- The tissue blood flow rate is calculated using dynamic scattering.
Industrial Perspective:
- The device and system is the integration of illumination with lensed image fiber that makes the entire system cost effective & may open up avenues for integration of other optical modalities for better tissue discrimination.
Questions about this Technology?
Contact for Licensing
Research Lab
Prof. Sujatha N
Department of Applied Mechanics and Biomedical Engineering,
Intellectual Property
- IITM IDF Ref.:1663Â
- Patent Application No. 201841006754
Technology Readiness Level
TRL-4
Proof of Concept, Tested & Validated