• This invention is the lack of a cost-effective and versatile preclinical imaging system capable of performing multiple imaging modalities (Radiography, CT, Fluoroscopy, XEOL, Fluorescence) using a single setup.
• The system that combines low cost with high resolution, utilizing advanced scintillator and CMOS camera technology to enable efficient and multi-modal imaging for preclinical studies.

Inorganic Scintillator (Cesium Iodide doped with Thallium – CsI (Tl)):

• Utilized as the X-ray detector material, it offers enhanced resolution compared to traditional phosphor screens.

High Frame Rate CMOS Camera:

• Employed for capturing images with high-speed frame rates, facilitating real-time dynamic imaging such as fluoroscopy

Multi-Modal Imaging Setup:

• The invention integrates various imaging modalities (Radiography, CT, Fluoroscopy, XEOL, Fluorescence) into a single system, eliminating the need for separate setups and costly equipment.

Automated Setup Transformation:

• The system enables easy transformation between imaging modalities by removing the scintillator and placing filters, enhancing flexibility and efficiency.

X-ray Excited Optical Luminescence (XEOL) and Fluorescence Imaging:

• By substituting the scintillator with filters, the system allows for X-ray-excited luminescence and fluorescence imaging.

Cost-Effective Design:

• The combination of advanced scintillator technology and high-resolution CMOS cameras provides cost-effective yet versatile imaging capabilities for preclinical studies.