Industrial Consultancy & Sponsored Research (IC&SR) , IIT Madras

A Spinning Disc Atomization Apparatus for Producing Micro-particles and a Method thereof

Technology Category/Market

Technology: Spinning disc atomization apparatus;

Industry: Food & Drug, Pharmaceutical; Applications: Micro-particle synthesis and drug encapsulation process;

Market: The global micro-encapsulation market size is projected to be valued $15.5B by 2025, CAGR of (12.9%) during period (2022-2025).

Image

Problem Statement

  • Atomization is a process of breaking a liquid solution into small droplets & then to produce micro-particles such as metal powders/alloys, wherein the types of atomization are carried out based on the type of fluid being used like centrifugal atomization & other types.
  • In the conventional process, the production of micro-particles are used for mass production & the size of the micro-particles typically≥100 microns which are fluidized & dried.
  • However, the broader sized of micro-particles are not suitable for synthesis of micro-particles for drug encapsulation, wherein the requirement is uniform sized & narrow size distribution of micro-particles.
  • This Invention provides solution of said issues.

Technology

  • Present invention describes a spinning disc atomization apparatus for producing micro-particles, shown in Fig. 1 & 2.
  • Said apparatus comprises a 1st enclosure configured to receive & dispense a feed solution, a 2nd enclosure defines a collection area, a base supporting 1st & 2nd enclosure, at least one slit defined for each of the 1st & 2nd enclosures to dispense a predefined volume of micro-droplets into a precipitation chamber, including associated interlinked assemblies.
  • Further, the micro-droplets come in contact with an anti-solvent mixture in the precipitation chamber to form solid microparticles of narrow size distribution. (Refer Figs. 3 & 4)
  • Nitrogen gas is supplied through connecting channels from a cylinder for drying & produce solid micro-particles.

Reference Nos listed hereinbelow:

100: Spinning disc atomization apparatus;

14: precipitation chamber; 16: feed vessel;

40: connecting channel(s);

1,2:First & second enclosure; 4:Rotating Disc;

26:Top cover through at least one first provision (24);

50: pressure regulator & gauge assembly;

3: portable oxygen and hydrocarbon analyzer.

Key Features/Value Proposition

Technical Perspective:

  1. Proposed apparatus & method describes the operation of production of micro-particles uniform size distribution limited to moderate to large production rate.
  2. Produced micro-particles with average sizes range ≥50 micron used for synthesis & drug encapsulation.

Industrial Perspective:

  1. Cost-effective & user-friendly apparatus.
  2. Feasible to separate the droplets based on size of micro-particles in a controlled manner.
Questions about this Technology?

Contact for Licensing

Research Lab

Prof. Raghunathan Rengaswamy

Prof. Basavaraj Madivala Gurappa

Dept. of Chemical Engineering

Intellectual Property

  • IITM IDF Ref.:2412;

  • Patent Application No:202241058428

Technology Readiness Level

TRL- 3/4

Proof of Concept & validated

error: Content is protected !!