Industrial Consultancy & Sponsored Research (IC&SR) , IIT Madras

Dental Composite Formulations

Technology Category/Market

Category – Medical and Surgical Devices

Applications –Dental cements,restorative dentistry, polymeric materials

Industry – Dental/ medical

Market -The global dental fillings market size was valued at USD 5.2 billion in 2018 and is expected to grow at a compound annual growth rate (CAGR) of 7.2% from 2019 to 2026.

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Problem Statement

  • Polymeric biomaterials are used in dental composites as restorative materials or adhesives for cavity filling , gap filling reshaping of teeth etc.
  • Conventional dental composites has disadvantages due to polymerization shrinkage, seepage of fluids and microorganism to pulp tissue ,diluents contributing to greater elution and cytotoxicity, post operative sensitivity, endocrine disruption etc.

Technology

The invention discloses a dental composite comprising:

A matrix comprising a hybrid of two macromers with

  1. Any of the many methacrylate terminal groups
  2. Any of the many ring-opening polymerizable group
  • Co-polymerization of the hybrid with any of the many biologically and chemically compatible            cross-linkers and plurality of adhesive monomers
  • Photoinitiator compounds
  • Hydrogen donor
  • Unsilanized filler
  • Additives

Matrix further comprises:

  • The Macromer resin “a” has a first functional moiety “b” and Macromer resin “c” has a second functional moiety “d”
  • The polymerizable monomers are represented as “e”, “f” and “g” as shown in the Fig. 1

Preparation of the Organic resin matrix

  • The constituents are mixed in a cyclic mixer to obtain a homogeneous product
  • To the above product 1% to 2% diketone, photoacid and a hydrogen donor are added and mixed in a cyclic mixer and stored in a brown/black container
  • Adding 1% to 2% of acidic monomer (dipentaerythritol pentaacrylate phosphoric acid ester (PENTA)), acid like butane tetracarboxylic acid, and hydrophilic monomer like hydroxyethyl methacrylate (HEMA) in a tertiary butanol vehicle
  • Obtaning the organic resin matrix

Composition of Dental composite

  • The dental composition includes the organic resin matrix combined with unsilanized filler
  • It can be 20-35% of organic resin matrix and 65-80% of unsilanized filler;  or at a range of 30% of the prepared organic resin matrix and 70% unsilanized Quartz filler

Key Features/Value Proposition

Technical Perspective:

  • Provide a novel dental composite ,that includes a composition for organic resin matrix and filler modification for polymeric biomaterial
  • Moderate self adhesive nature minimizes the use of unfilled bonding agents which may increase post-operative sensitivity and cytotoxixity
  • The matrix shrinks less as predominant polymerization is based on ring opening
  • Composition satisfies the concept of increased ratio of molar volume to number of double bonds.

User Perspective:

  • Highly hydrophobic, good crosslinking ,low elution, biocompatible and hydrolytically stable
  • Used for cementation of implants, endodontic sealers, root repair materials, root end filling materials, and luting cements
  • The first functional moiety “b” includes at least one of a free-radical polymerizable Methacrylate group and the second functional moiety “d” includes at least one of a ring-opening polymerizable cyclic Epoxy group
  • The additives of the said composite comprises stabilizer, inhibitor, coloring pigments, oxygen scavengers, antibacterial, anti-caries agents, others that induce smart properties by one of self-healing, repair, and debonding
  • Photoinitiator can be diketone or a propanedione or an acylphosphene oxide or any one Norrish Type II photoinitiator
  • Adhesive monomers are mixture of an acid ester, acid, and hydrophilic monomer
Questions about this Technology?

Contact for Licensing

Research Lab

Prof. Venkatesh Balasubramanian

Department of Engineering Design

Intellectual Property

  • IITM IDF Ref. 975
  • IN343192-Granted
  • PCT/IN2014/000408

Technology Readiness Level

TRL- 4

Technology Validated in lab

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