Industrial Consultancy & Sponsored Research (IC&SR) , IIT Madras
Method for Synthesis of Nanocomposites by Microbes
Categories for this Invention
Category – Biomedical Engineering, Tissue Engineering
Applications – Bone Tissue Engineering, Medical Implants.
Industry – Biomedical, Materials Science, Healthcare Industry.
Market – Global Bioengineering Technology Market size was valued at USD 239.1 Bn in 2022 and the Bioengineering Technology Market revenue is expected to grow at a CAGR of 12.3 % from 2023 to 2029.
Image Gallery
Problem Statement
- Bone tissue engineering faces challenges in developing strong, vascularized scaffolds; existing polymer-based substitutes lack bioactivity and struggle to mimic natural bone structure.
- This invention includes cost-effective, biomimetic bone substitutes and solutions promoting enhanced bone regeneration and integration, demanding innovative approaches leveraging natural materials and microbial processes.
Technology
Microbial Nano cellulose:
- Utilizes microbial synthesis from bio-tea to produce Symbiotic Colony of Bacteria and Yeast(SCOBY), a low-cost source of Nano cellulose.
Hydroxyapatite Deposition:
- Deposition onto Nano cellulose mimics natural bone formation for enhanced biomimetic properties.
Bone Tissue Engineering:
- Leverages nanotechnology for strong, porous scaffolds addressing bone defects
Bacterial Synthesis:
- Employs Serratia marcescens to synthesize carbonated hydroxyapatite resembling natural bone composition.
Nanocomposite Fabrication:
- Integrates Nano cellulose and hydroxyapatite, aligning rod-shaped crystals to mimic bone structure.
Key Features / Value Proposition
User Perspective:
- Surgeons and patients benefit from innovative nanocomposites during surgeries, improving outcomes and accelerating bone healing.
- Patients with bone injuries gain faster recovery and better quality of life with biomimetic scaffolds supporting natural bone regeneration.
Technical Perspective:
- Researchers focus on efficient synthesis and characterization of microbial Nano cellulose, ensuring mechanical strength and biocompatibility.
- Optimization of hydroxyapatite deposition techniques and evaluation of resulting nanocomposites’ properties are crucial for bone tissue engineering.
Questions about this Technology?
Contact For Licensing
sm-marketing@imail.iitm.ac.in
ipoffice2@iitm.ac.in
Research Lab
Prof. Chandra T S
Department of Biotechnology
Prof. Sampath Kumar T S
Department of Metallurgical and Materials Engineering
Intellectual Property
- IITM IDF Ref. 1731
- IN 402779 (Patent Granted)
Technology Readiness Level
TRL- 4 Technology validated in lab scale.