Industrial Consultancy & Sponsored Research (IC&SR) , IIT Madras

Image-Free Ultrasound for Non-Invasive Assessment of Early Vascular Health Markers

Technology Category/ Market

Industry: Life Science, Medical and Surgical Equipment, Transducers & Sensors,

Applications: Ultrasound System, Hospitals

Market: The global ultrasound transducer market size was valued at USD 3.2 B in 2018; is expected to expand at 3.6% CAGR by 2026.

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Problem Statement

  • Early detection and timely intervention helps in reducing the mortality and morbidity in the cardiovascular disease. Currently age, family disease history, dyslipidemia, diabetes, central obesity etc. gives an indirect hint of the development and progression of the disease in the blood vessels and the heart.
  • The earliest sign is endothelium functional changes that controls dynamic ability of the blood vessel to regulate the vessel wall stiffness in response to autonomic regulatory activity of body.
  • Loss of endothelial function leads to increased stiffness of the vessel wall, increased wall thickness and plaque formation, in time leading to an adverse cardiovascular and cerebrovascular event like angina, ischemia, heart failure, stroke.
  • However, the routine clinical use of such markers is hampered by the lack of easy-to-use technology for reliable non-invasive assessment at low price.
  • The present patent addresses above mentioned issues with an image-free ultrasound system.

Technology

The present patent discloses an image-free ultrasound system to provide a comprehensive evaluation of vascular health by performing the non-invasive assessment of endothelial function, local vascular stiffness at any superficial artery, and regional vascular across an arterial segment. The system consists of a compact, easy-to-use, field-deployable ultrasound device that does not construct any form of ultrasound images.

Key Features/ Value Proposition

  • Detects early markers that indicate vascular stiffness, both local and regional, in routine clinical diagnostic practices.
  • especially inbuilt with provisions for easy-to-use, minimal operator dependency, portability, and field deployability.
  • the present disclosure may take the form of an entirely hardware embodiment, a software embodiment or an embodiment combining software and hardware aspects.

Questions about this Technology?

Contact for Licensing

sm-marketing@imail.iitm.ac.in
ipoffice2@iitm.ac.in

Research Lab

Prof. Jayaraj Joseph 

Department of Electrical Engineering

Prof. Mohanasankar Sivaprakasam

Department of Electrical Engineering

Intellectual Property

  • Application Number: 202041013190
  • IITM IDF Ref. 2063

Technology Readiness Level

TRL- 4

Proof of Concept ready, tested and validated in Lab.

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