Industrial Consultancy & Sponsored Research (IC&SR) , IIT Madras
Microfluidic Device and Method of Manufacturing thereof
Technology Category/ Market
Technology: Microfluidic Device.
Industry: Pharmaceutical, Medical device.
Applications: Medical Device.
Market: The global microfluidics market is projected to grow at a CAGR of 12.22% during 2024-2030.
Image Gallery
Problem Statement
- In the present era, it is noted that there are significant challenges in the ultra-purification of blood associated with the device used in the diffusion process, being bulky, time-consuming, and involving high cost.
- The present invention addresses the technical problem stating how to provide bio-compatible microfluidic devices for ultra-purification of blood that overcome the limitation of ionic imbalance and also a method of fabrication of the micro-features of the microfluidic devices using high-quality masters.
- Hence, the present invention provides the solution to the above issues in an efficient manner.
Technology
- The present invention describes a microfluidic device which operates on deterministic lateral displacement through micropillars which is used to separate blood cells from plasma.
- Further present invention discloses about the fabrication of polymeric bio microfluidic devices for ultra purification of blood, i.e. application of femtosecond lasers for the fabrication of the masters.
- The microfluidic device comprises at least one deterministic Lateral Displacement (DLD) assembly for filtering one or more constituents in the bloodstream.
- The DLD assembly comprises micro-structures formed in micro-channels.
- The bloodstream passing through the micro-structures is separated into a first bloodstream comprising blood plasma with potassium (K+) ions and a second bloodstream containing blood cells.
- A diffusion assembly comprises a buffer inlet for intake of a buffer solution containing sodium (Na+) ions, a cellulose membrane receiving the buffer solution and the first bloodstream.
Key Features/ Value Proposition
Technical Perspective:
- Provides a low-cost & portable microfluidic device for ultra-purification of blood, and method of fabrication thereof.
- Provides a method of fabrication of micro-features of the microfluidic device using high-quality masters.
- Fabricate a microfluidic device for efficient ionic separation in fluids, such as blood, to maintain ionic balance in the bloodstream.
Industrial Perspective:
- Fabricate cost-effective high throughout and bio-compatible microfluidic device for ultra-purification of blood and method of fabrication thereof.
Questions about this Technology?
Contact for Licensing
sm-marketing@imail.iitm.ac.in
ipoffice2@iitm.ac.in
Research Lab
Prof. Samuel G L
Department of Mechanical Engineering
Intellectual Property
IITM IDF Ref. 2289
IN Patent No: 469660
Technology Readiness Level
TRL-3/4
Proof of Concept ready, tested in lab.