Industrial Consultancy & Sponsored Research (IC&SR) , IIT Madras
Environmentally Benign Reusable Copper Nanoparticles-catalyzed Synthesis of Thiochromanones in Water
Technology Category/Market
Category – Chemistry/Chemical Synthesis
Applications -Chemical research and development, Pharmaceutical Industry, Green chemistry, Nanoparticle applications, Environmental-friendly chemical processes.
Industry – Chemicals, Pharmaceuticals, Organic Synthesis.
Market -The global Organic Catalyst Market size was USD 37.5 billion in 2022 and is estimated to grow to USD 54.77 billion by 2030. This market is witnessing a healthy CAGR of 4.85% from 2023 – 2030.
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Problem Statement
- Conventional synthesis of thiochromanones is inefficient and time-consuming, involving toxic and hazardous reagents, leading to high waste production and environmental impact.
- There is a demand for an efficient and environmentally friendly method to synthesize thiochromanones, requiring a recoverable and reusable catalyst.
- The development of a process utilizing water as a solvent reduces waste and improves sustainability while providing high yields of thiochromanones and easy handling of starting materials.
Technology
- The invention introduces a novel heterogeneous copper binaphthyl nanoparticle (Cu-BNP) catalyst for thiochromanone synthesis.
- The heterogeneous Cu-BNP catalyst wherein the size of the copper nanoparticle is 3.5-5nm.
- Green and sustainable process using water as a solvent, reduces the environmental impact.
- Easily recoverable and reusable catalyst contributes to a more sustainable chemical synthesis process.
- The catalyst can be employed in the synthesis of various thiochromanones and their derivatives, making it applicable in pharmaceuticals, chemicals, and other research fields.
- The starting materials and reaction conditions are easy to handle, simplifying the overall process and making it accessible to researchers and practitioners in the field.
- Efficient catalyst recovery, enhancing its economic feasibility and minimizing waste generation.
- The invention allows for the synthesis of different thiochromanone derivatives.
- The method employs odorless potassium ethyl xanthate as a sulfur source, wherein TBA●HSO4 is used as a phase transfer catalyst in water at 80oC, reducing the risk of exposure to toxic and hazardous reagents.
Key Features/Value Proposition
Technical Perspective:
- The heterogeneous Cu-BNP catalyst enables efficient synthesis of thiochromanones in water, offering a green and safe alternative to traditional methods. Easy recovery and reusability make it cost-effective and environmentally friendly.
User Perspective:
- The Cu-BNP catalyst presents a competitive advantage for thiochromanone production, with high yields and reduced environmental impact. Its versatility and regulatory compliance make it an attractive option for various industries.
Questions about this Technology?
Contact for Licensing
Research Lab
Prof. G. Sekar
Department of Chemistry
Intellectual Property
- IITM IDF Ref. 2244
- IN 415562 (PATENT GRANTED)
Technology Readiness Level
TRL- 3
Proof of concept established.