A Method of Detection of Low Concentration of Analytes by Superhydrophobic Pre-concentration Paper Spray Ionization Mass Spectrometry (SHPPSI MS)
Categories for this Invention
Technology: Detection of low concentration of analytes by superhydrophobic pre-concentration paper spray ionization mass spectrometry (SHPPSI MS)
Industry & Application:. Food Industry, Milk Industry & etc.;
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Problem Statement
- The problem statement discussed in the present subject matter is how to achieve spontaneously on a superhydrophobic (SHP) paper.
- Hence, Present invention provides the solution in efficient manner.
Technology
- Present patent describes a method namely SHPPSI MS which combines pre-concentration and ionization on the substrate, useful in many analytical situations. (Refer Fig. 1)
- The claimed subject matter relates to a simultaneous pre-concentration cum ionization method for the analysis of analytes in solutions combined on a paper, wherein the pre-concentration is achieved by having a hydrophobic coating on the paper and with a point defect made at the tip of the paper.
- Applicable for the detection of analyte at extremely low levels down to picomolar and lower in complex mixtures.
Key Features / Value Proposition
- Facilitates a new ambient ionization method called superhydrophobic preconcentration paper spray ionization mass spectrometry (SHPPSI MS) where a preconcentration technique is coupled with paper spray mass spectrometry.
- More specifically, provides superhydrophobic coating on a paper spray source with localized sample deposition, preconcentration, and elution combined with mass spectrometry.
- The pre-concentration is achieved by surfaces with water contact angle ≥ 900 and hexane contact angle ≥ 900
- The ions are detected by mass spectrometer, Faraday cups and ion mobility spectrometers
Questions about this Technology?
Contact For Licensing
sm-marketing@imail.iitm.ac.in
ipoffice2@iitm.ac.in
Research Lab
Prof. Pradeep T
Department of Chemistry
Intellectual Property
IITM IDF Ref. 1640
Patent No. 504588
Technology Readiness Level
TRL-4
Technology validated in Laboratory